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For a couple trying to conceive, a diagnosis of “unexplained infertility” is difficult to receive. It’s also more common than you might expect. One in every three couples who seek fertility treatment has been diagnosed as “unexplained”. Unexplained infertility does not mean that there is no cause for infertility but rather that the cause has not yet been discovered.

Many scientists believe that unexplained infertility has a genetic basis that involves the eggs, sperm, or both. Fertility treatments such as IVF and preimplantation genetic diagnosis (PGD) provide a more detailed picture of how the egg and sperm interact and ultimately how the embryo develops.

As research progresses, fewer and fewer couples will fall into the category of unexplained infertility. Perhaps the best news is that more than 80% of couples who consult a reproductive endocrinologist will become pregnant.

What is the definition of unexplained infertility?
If my infertility is unexplained, how do I know what treatment is best?
Are there any medications I can take if I am diagnosed with "unexplained infertility"?